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In one week managers might need to hire staff to accommodate an intimate black-tie dinner party for 30 diners, a 3,000-person corporate event and a promotional cocktail hour for 300 people.Finding talented workers during busy periods, retaining them during slow periods, is both stressful and time consuming.(NASDAQ: APLS), a clinical-stage biopharmaceutical company focused on the development of novel therapeutic compounds to treat disease through the inhibition of the complement system, today announced the closing of its initial public offering of 10,714,000 shares of common stock at a public offering price of .00 per share.The total gross proceeds to Apellis were approximately 0.0 million, before deducting underwriting discounts and commissions and expenses payable by Apellis. In addition, Apellis granted the underwriters a 30-day option to purchase up to 1,607,100 additional shares of common stock at the public offering price, less underwriting discounts and commissions, to cover over-allotments, if any. Morgan and Evercore ISI acted as joint book-running managers for the offering. 15, 2017 (GLOBE NEWSWIRE) — Nu Cana plc (NASDAQ: NCNA) announced the enrollment of the first patients in both the United States and the United Kingdom in its PRO-105 study evaluating single-agent Acelarin (NUC-1031) in patients with platinum-resistant ovarian cancer.

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SYNB1020, is a novel, first-in-class, Synthetic Biotic medicine that is orally delivered and designed to treat elevated blood ammonia levels, or hyperammonemia, in genetic urea cycle disorders (UCD) or in chronic liver disease “The positive data from our Phase 1 study in healthy volunteers, demonstrates that SYNB1020 was well-tolerated and had a statistically significant dose-dependent effect on the level of a nitrogen endpoint, providing evidence to support its mechanism of action,” said Aoife Brennan, M. D., Synlogic’s president and chief executive officer.

Acelarin achieved a disease control rate of 93% in a subset of 14 evaluable patients with advanced gynecological cancers in the PRO-001 study.



“When they talk about going out on a typical cop’s job and wondering if they’re going to return at night — it brings a reality to that, something as seemingly simple as cleaning a highway,” said Cornish, a former law enforcement officer who planned to attend Mathews’ funeral Thursday.… continue reading »


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